HCG (human chorionic gonadotropin) is a glycoprotein hormone produced by placental syncytiotrophoblast cells, distinguishing it structurally from the smaller peptides elsewhere in our catalog. At approximately 37 kDa, hCG is a heavily glycosylated, two-subunit molecule rather than a short amino acid chain, though it is conventionally grouped alongside research peptides due to overlapping use cases in reproductive biology research.
HCG's primary mechanism is activation of the LH/hCG receptor (LHCGR), the same G protein-coupled receptor also activated by luteinizing hormone (LH). Despite sharing a single receptor, hCG and LH have been shown to produce distinct intracellular signaling outcomes, a phenomenon known as biased agonism, where structural differences between the two hormones (particularly in the receptor-binding loop) lead to differing cAMP and ERK1/2 activation kinetics. This receptor-sharing, signal-biasing relationship makes hCG a frequently studied tool in reproductive endocrinology and GPCR signaling research, particularly for distinguishing hormone-specific signaling from purely receptor-mediated effects.
Product Specifications
Purity: >99%, verified via HPLC
Form: Lyophilized powder
Vial Size: Multi-dose vial (supports up to 3ml reconstitution)
Reconstitution & Storage
Intended Use: For laboratory research purposes only. Reconstitution with Bacteriostatic Water (BAC water) is required before use.
Storage: Store lyophilized powder in a cool, dry place away from light. After reconstitution, keep refrigerated at 2-8°C.
Solubility: Reconstitute with BAC water. Gently swirl to dissolve, do not shake.
Shelf Life: Lyophilized form has a shelf life of up to 24 months. Once reconstituted, recommended use within 4-6 weeks.
Handling: Use sterile techniques to maintain product stability and integrity.
Important Notice
This product is intended for laboratory and research use only. It is not for human or veterinary consumption, and is not approved for use as a food, drug, cosmetic, or household chemical. Baldena Biolabs does not condone or support self-administration of this product. By purchasing, you confirm you are a qualified researcher or research institution and accept full responsibility for safe and legal handling in accordance with applicable laws.
